The United States Pharmacopeia (USP) defines delayed- release tablets as enteric-coated to delay release of the med ication until the tablet has passed through the stomach to prevent the drug from being destroyed or inactivated by gastric juices or where it may irritate the gastric mucosa.Jul 23, 2007

Is enteric-coated controlled release?

In such cases, enteric-coated tablets and capsules are used for controlled release of drugs. … Furthermore, it may be necessary for the drug to pass through the low pH stomach fluids and be released at higher pH in the intestinal tract.

What is meant by enteric-coated?

Enteric-coated: Coated with a material that permits transit through the stomach to the small intestine before the medication is released. The term "enteric" means "of or relating to the small intestine."

What is difference between delayed release and enteric-coated?

Small, delayed-release multi-units enable them to empty readily from the stomach into small intestine, thus facilitating rapid drug dissolution, absorption, and onset of action. Enteric-coated tablets take longer time to empty into the intestine.

What is the difference between extended-release and delayed release?

Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).

Are enteric-coated tablet extended-release?

USP defines extended-release tablets “formulated in such a manner to make the contained medicament available over an extended period of time following ingestion.” Both the delayed-release and extended-release formulations of De pakote are enteric-coated but not interchangeable.

How long does it take enteric aspirin to dissolve?

It varies from 30 minutes up to 7 hours, with an average time of 6 hours.

What is delayed release mean?

Medical Definition of delayed-release : designed to delay release of a drug in the body (as through the use of enteric coatings) usually until it passes through the stomach into the small intestine … the effects of the ingestion of delayed-release preparations may not be fully manifested for hours.—