Soundness of mind

Does NyQuil make you feel tired the next day?

How long do the sedative effects of NyQuil last?

The sedative effects of NyQuil usually last 4–6 hours. However, the exact duration of effects may vary depending on the individual and other factors such as age, weight, and metabolism. It is important to note that NyQuil may cause drowsiness and impaired judgment, so it is important to follow the manufacturer’s instructions when taking the medication and to not drive or operate machinery after taking it.