What is the role of calcium and phosphate in bone?
Among micronutrients, calcium (Ca) and inorganic (i) phosphate (P) are the two main constituents of hydroxyapatite, the bone mineral that strengthens the mechanical resistance of the organic matrix. … Pi plays a role in the maturation of osteocytes, the most abundant cells in bone.
What is the role of phosphate in bone?
The presence of phosphate is crucial for bone growth and mineralization and in its absence in sufficient amounts, rickets and osteomalacia will develop. The maintenance of optimal phosphate balance is managed by complex interactions between the gut, kidney, and bone, involving multiple regulators.
What is the role of calcium in bones?
Calcium is the major component of the bone, where it is present at more than 99% as calcium-phosphate complexes, and provides the skeleton strength and structure, making the bone a metabolic reservoir to maintain the intra- and extra-cellular calcium pool.
What is the relation between calcium and phosphate?
The amount of phosphate in the blood affects the level of calcium in the blood. Calcium and phosphate in the body react in opposite ways: as blood calcium levels rise, phosphate levels fall. A hormone called parathyroid hormone (PTH) regulates the levels of calcium and phosphorus in your blood.
What is the purpose of phosphorus?
About 85% of the body's phosphorus is in bones and teeth. Phosphorous is also present in smaller amounts in cells and tissues throughout the body. Phosphorus helps filter out waste in the kidneys and plays an essential role in how the body stores and uses energy.
Does calcium help bone density?
Children need calcium to build strong bones. Adults need calcium to maintain strong bones. Over time, inadequate calcium intake can cause osteoporosis, the brittle bone disease. People with osteoporosis are at high risk for broken bones, especially at the wrist, hip and spine.
What is the use of phosphorus?
Function. The main function of phosphorus is in the formation of bones and teeth. It plays an important role in how the body uses carbohydrates and fats. It is also needed for the body to make protein for the growth, maintenance, and repair of cells and tissues.
What are the advantages of phosphorus?
The body uses phosphorus to keep the bones strong and healthy. Phosphorus also helps remove waste and repair damaged tissues. Most people get enough phosphorus through their diet. However, people with certain health conditions, such as kidney disease or diabetes, may need to adjust their phosphorus intake.