Reported improvement (e.g. reduction in painful symptoms) varies from three weeks to as much as eight weeks. Some studies have shown continued improvement of symptoms after oral intake was stopped. Generally, if there is no pain reduction after two months, there is little chance of improvement.

How long does it take for glucosamine to start working?

It can take four to eight weeks for glucosamine sulfate to ease pain.

Does glucosamine supplement really work?

Generally safe Glucosamine sulfate might provide some pain relief for people with osteoarthritis. The supplement appears to be safe and might be a helpful option for people who can't take nonsteroidal anti-inflammatory drugs (NSAIDs). While study results are mixed, glucosamine sulfate might be worth a try.

What time of day should glucosamine be taken?

Generally, glucosamine should be taken with meals three times per day. Doses usually range from 300–500 mg with each meal, adding up to a total daily dose of 900–1,500 mg. Most studies used 1,500 mg per day.

Can glucosamine make joints worse?

The study was stopped early for an unusual reason — those taking the supplement actually reported worse symptoms than those taking a placebo. This raises the possibility that taking glucosamine and chondroitin might make your joints feel worse than doing nothing.

Does glucosamine increase weight?

Results: GlcN administration stimulated body weight gain (6.58±0.82 g vs. 11.1±0.42 g), increased white adipose tissue fat mass (percentage of bodyweight, 3.7±0.32 g vs. 5.61±0.34 g), and impaired the insulin response in livers of mice fed CD.

Does glucosamine help arthritis in hands?

Newsum says that there's moderate scientific evidence to show that the over-the-counter supplement glucosamine chondroitin may be helpful in alleviating the symptoms of arthritis. This is because glucosamine and chondroitin are natural components of cartilage, which is the tissue that cushions all of the body's joints.

Does glucosamine make you gain weight?

Results: GlcN administration stimulated body weight gain (6.58±0.82 g vs. 11.1±0.42 g), increased white adipose tissue fat mass (percentage of bodyweight, 3.7±0.32 g vs. 5.61±0.34 g), and impaired the insulin response in livers of mice fed CD.